Robert Gifford
This Bieniasz lab paper convincingly shows shows that the SARS-COV2 nuclease NSP15 can drive insertional mutagenesis. The mechanism is plausible and elegantly demonstrated. But the conclusion that the SARS-CoV-2 FCS is "an example of such an event" is not supported by the data.
Paul Bieniasz
Our new preprint on the origin of insertion mutations (including furin cleavage sites) in coronaviruses
