The Lancet

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A genetically modified pig kidney kept a man off dialysis for nine months before a successful human kidney transplant, according to a world-first report in The Lancet. Read now: https://spkl.io/60107RycO

Figures showing (A) Total daily urine output (mL) during the first week after xenotransplantation. (B) Serum creatinine and eGFR throughout the xenograft period. Note that scales on y axes differ between plots. Vertical dashed lines indicate for-cause kidney biopsies\u2014key histopathological findings are annotated: day 14, Banff IIA TCMR; day 176, MVI with endothelial injury; day 264, TMA with transplant glomerulopathy. (C) Serum sodium. (D) Serum potassium. All panels share a common x-axis representing days relative to xenotransplantation (day 0). eGFR=estimated glomerular filtration rate. MVI=microvascular inflammation. TCMR=T-cell-mediated rejection. TMA=thrombotic microangiopathy. Copyright: 2026 Elsevier Ltd. All rights are reserved.