Among NB.1.8.1 sub-lineages, the fastest one is designated PQ.2 today. PQ.2 is 30% faster than NB.1.8.1 and reached 30% in Hong Kong. It gains Orf3a:W193R, one of the key residues deciding different functions of Orf3a in SARS-1(R) and SARS-2(W). https://github.com/cov-lineages/pango-designation/issues/2954