From a case-control study of 83 primary multiple sclerosis (MS) patients and 100 healthy controls, "Serum IL-6 and TNF-α levels were significantly higher in the frail group than in the non-frail group.. serum IL-6 independently correlated with frailty in MS patients.. Our initial findings suggest elevated levels of pro-inflammatory cytokines [like IL-6] in MS patients with frailty.." Increase of IL-6 level has been commonly observed after SARS-CoV-2 infection. 'Association between frailty and inflammatory cytokines in patients with multiple sclerosis: a case-control study' https://www.sciencedirect.com/science/article/pii/S1043466625000924
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